Prediction of coding potential
Periodicity detection
- Coding sequences have an inherent periodicity of three
- Especially good on long coding sequences
- Auto-correlation
- Seeking the strongest response when shifted sequence is compared with original
- Michel (1986), J. Theor. Biol. 120, 223-236.
- Fourier transformation: Spectral analysis
- Detection of peak at position corresponding to 1/3 of the frequency
- Silverman and Linsker (1986), J. Theor. Biol. 118, 295-300.