Conclusions on annotating complete eukaryotic genomes
Throughput has to improve dramatically
Not only genes but also their relationships have to be elucidated
Complete transcript cDNAs very powerful tool for annotation including alternative transcripts
Comparative genomics as well as expression analysis improves/completes genome annotation
Standardization efforts needed (ontology working group, OMG, OiB, NCBI/EBI, Bioxml, etc.)
- Standards for description of gene products
- Exchange format (GFF, Genbank, EMBL, XML)