“Integrated” gene models: GHMMs

• GenScan

  • Multiple content and signal models
  • Semi-hidden Markov model sensors with length distribution
  • Takes GC content into account (separate models)
  • Several genes per sequence possible
  • Burge and Karlin (1997), JMB, 268(1), 78-94.
  • http://CCR-081.mit.edu/GENSCAN.html

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