EST/cDNA alignment for gene finding: Spliced alignments

• PROCRUSTES

  • Spliced alignment algorithm
  • Dynamic programming to combine a set of potential exons
  • Frame conservation
  • Homologous sequence needed
  • Gelfand et al. (1996), PNAS, 93, 9061-9066.
  • http://hto-13.usc.edu/software/procrustes/

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